Xiufeng Li1, Subhendra N. Sarkar2, David E. Purdy3, Robert W. Haley4, Richard W. Briggs1,4
1Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 2Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 3Siemens Healthcare, Malvern, PA, United States; 4Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States
To facilitate reliable and sensitive perfusion measurements in the sub-regions of the hippocampus, we developed OPTIMAL FAIR (orthogonally positioned imaging tagging method for arterial labeling with FAIR) and performed comprehensive optimization studies for the proper selection of arterial spin labeling parameters. Study results indicated that the anterior segment of the hippocampus has different blood flow dynamic characteristics from the other parts of the hippocampus, e.g. the lowest perfusion and the longest transit time, which can be due to different sources of arterial blood supply.