Xiufeng Li1, Subhendra N. Sarkar2,
David E. Purdy3, Robert W. Haley4, Richard W. Briggs1,4
1Radiology, UT Southwestern Medical
Center, Dallas, TX, United States; 2Radiology, Beth Israel
Deaconess Medical Center, Boston, MA, United States; 3Siemens
Healthcare, Malvern, PA, United States; 4Internal Medicine, UT
Southwestern Medical Center, Dallas, TX, United States
To
facilitate reliable and sensitive perfusion measurements in the sub-regions
of the hippocampus, we developed OPTIMAL FAIR (orthogonally positioned
imaging tagging method for arterial labeling with FAIR) and performed
comprehensive optimization studies for the proper selection of arterial spin
labeling parameters. Study results indicated that the anterior segment of the
hippocampus has different blood flow dynamic characteristics from the other
parts of the hippocampus, e.g. the lowest perfusion and the longest transit
time, which can be due to different sources of arterial blood supply.
Keywords