Rebecca Susan Dewey1,2, Dorothee P. Auer1, Susan T. Francis2
1Division of Academic Radiology, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom
Watershed areas are brain regions supplied by the most distal branches of the cerebral arteries and are most susceptible to haemodynamic ischaemia. We assess the use of territorial ASL to define Left and Right Internal Carotid, Anterior Cerebral, and Basilar Artery territories to distinguish the watershed area, and assess its correspondence with haemodynamic parameters (perfusion rate, arterial blood volume and arterial and tissue transit times) from multiphase ASL. Specified anatomical regions are assessed for vascular supply and haemodynamic parameters. Combining these techniques, an atlas of parameters can be formed for region-specific perfusion and position and functional effects of watershed areas.