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Abstract #1818

Fat Temperature Imaging with T1 of Fatty Acid Species Using Multiple Flip Angle Multipoint Dixon Acquisitions

Kagayaki Kuroda1,2, Taku Iwabuchi, Mie Kee Lam3, Makoto Obara4, Masatoshi Honda5, Kensuke Saito, Marc Van Cauteren4, Yutaka Imai5

1Graduate School of Engineering, Tokai University, Hiratsuka, Kanagawa, Japan; 2Medical Device Development Center, Foundation for Biomedical Research and Innovation, Kobe, Hyogo, Japan; 3Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands; 4MR Marketing, Philips Electronics Japan Medical Systems, Shinagawa, Tokyo, Japan; 5Department of Radiology, Tokai University, Isehara, Kanagawa, Japan

A fat temperature imaging technique based on multiple flip angle, multipoint Dixon acquisitions and a least square estimation scheme is proposed. Gradient recalled acquisition of 5 echo times with 3 different flip angles were obtained to separate the signals of methylene and methyl protons and to estimate T1's of these fatty acid species. Temperature images of a water-oil phantom were successfully obtained with previously obtained temperature coefficients demonstrating the feasibility of quantitative thermometry of fat. Since the acquisition time was 4-6 second, the technique seemed to be practical for temperature monitoring of fat-water tissues like breast under thermal therapies.