Abstract #1850

4D Transcatheter Intra-Arterial Perfusion MR Imaging for Monitoring Uterine Artery Embolization in the Rabbit VX2 Tumor Model

Johnathan C. Chung¹, Robert K. Ryu¹, Dingxin Wang², Richard Tang¹, Reed A. Omary^2,3, Andrew C. Larson^2,3

¹Department of Radiology, Northwestern University, Chicago, IL, United States; ²Department of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, United States; ³Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, United States

Four-dimensional (4D) transcatheter intra-arterial perfusion (TRIP) MRI is a monitoring technique that involves targeted intra-arterial (IA) injections of gadolinium (Gd) (<0.001 mmol/kg) to help quantify volumetric tissue-perfusion changes over time. This technique can be used to objectively monitor tumor perfusion changes after UAE in VX2 rabbits. The technique may have future clinical application in optimizing endpoints during UAE.