Abstract #1866

Novel Perfluorooctylbromide Alginate Microcapsules for Enhanced Mesenchymal Stem Cells Survival and Noninvasive Imaging Using Clinical CT and 19F MRI

Yingli Fu¹, Dorota A. Kedziorek¹, Steven Shea², Yibin Xie¹, Ronald Ouwerkerk³, Gary Huang¹, Tina Ehtiati², Steffi Valdeig¹, Jeff WM Bulte^1,4, Frank Wacker¹, Dara Kraitchman¹

¹Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States; ²Imaging and Visualization, Siemens Corporate Research, Baltimore, MD, United States; ³National Institute of Diabetes and Digestiv and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States; ⁴Institute of Cell Engineering, Baltimore, MD, United States

To enable allogeneic mesenchymal stem cell therapy for peripheral arterial disease, we present here a novel perfluorootylbromide microcapsues that enhance cell survival and enable cell tracking using noninvasive clinical imaging modalities.