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Abstract #1866

Novel Perfluorooctylbromide Alginate Microcapsules for Enhanced Mesenchymal Stem Cells Survival and Noninvasive Imaging Using Clinical CT and 19F MRI

Yingli Fu1, Dorota A. Kedziorek1, Steven Shea2, Yibin Xie1, Ronald Ouwerkerk3, Gary Huang1, Tina Ehtiati2, Steffi Valdeig1, Jeff WM Bulte1,4, Frank Wacker1, Dara Kraitchman1

1Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States; 2Imaging and Visualization, Siemens Corporate Research, Baltimore, MD, United States; 3National Institute of Diabetes and Digestiv and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States; 4Institute of Cell Engineering, Baltimore, MD, United States

To enable allogeneic mesenchymal stem cell therapy for peripheral arterial disease, we present here a novel perfluorootylbromide microcapsues that enhance cell survival and enable cell tracking using noninvasive clinical imaging modalities.