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Abstract #1899

Multimeric Iron Oxide Micro Particles: Novel High Sensitivity and Biodegradable MRI Contrast Agents.

Francisco Perez-Balderas1, Benjamin G. Davis2, Sander van Kasteren2, Alexandr Khrapichev1, Daniel Anthony3, Nicola R. Sibson1

1CR-UK/MRC Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, United Kingdom; 2Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom; 3Department of Pharmacology, Univerity of Oxford, Oxford, United Kingdom

Biodegradable multimeric iron oxide microparticles were obtained by conjugation of iron oxide nanoparticles through peptides. These multimeric particles constitute an ideal platform for new highly sensitive and specific MRI contrast agents.