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Abstract #1925

Anti-IL17 Treatment Reduces Clinical Score and VCAM-1 Expression in EAE-ABH Mice Detected by in Vivo Magnetic Resonance Imaging

Sebastien Serres1, Silvy Mardiguian2, Martina A. McAteer3, Robin P. Choudhury4, Sandra J. Campbell5, Paul Smith6, Fay Saunders7, Nicola R. Sibson8, Daniel C. Anthony2

1Gray Institute for Radiation Oncology and Biology, Oxford, Oxon, United Kingdom; 2Department of Pharmacology, University of Oxford; 3Department of Cardiovascular Medicine; 4Department of Cardiovascular Medicine, University of Oxford; 5Department of Pharmacology, university of Oxford; 6Department of Pharmacology, UCB, Slough; 7Department of Antibody Biology, UCB, Slough,; 8Gray Institute for Radiation Oncology and Biology, University of Oxford

Anti-IL17 treatment reduces clinical score and VCAM-1 expression in EAE-ABH mice detected by in vivo magnetic resonance imaging