Meeting Banner
Abstract #1962

Parkinsons Disease and Imaging of the Substantia Nigra Structure with 7.0T MRI

Dae-Hyuk Kwon1, Hye-Jin Jeong1, Se-Hong Oh1, Jong-Min Kim2, Syung-Yeon Park1, Young-Bo Kim1, Beom-Seok Jeon2, Zang-Hee Cho1

1Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, Korea, Republic of; 2Movement Disorder Center, Seoul National University Hospital, Seoul, Korea, Republic of

T2* weighted MR image is influenced by iron deposition, so that SN shows up iron-related MRI contrast for all that SN is gray matter. Therefore T2* MR imaging shows great potential in PD study using ultra high field (UHF) 7.0T. And 3D T2* Gradient Echo (GE) sequence makes it possible to study a volumetric analysis and a structural morphometry for SN. This method is validated, despite the reduced SNR associated with fast imaging techniques. And 3D model of the SN shows quite well structural changes in PD case.