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Abstract #2012

Age-Related Effects on Resting State Default, Executive and Salience Networks Reveal Different Pruning Mechanisms a Resting State FMRI Study.

Vesa Kiviniemi1, Harri Littow1, Ahmed Abou-elseoud1, Katariina Mankinen2, Jukka Rahko3, Jukka Remes1, Juha Nikkinen1, Tuomo Starck1, Juha Veijola4, Christian Beckmann5, Osmo Tervonen1

1Diagnostic Radiology, Oulu University Hospital, Oulu, Finland; 2Pediatric department, Oulu University Hospital, Oulu, Finland; 3Child Psychiatry, Oulu University Hospital, Oulu, Finland; 4Psychiatry, Oulu University, Oulu, Finland; 5Clinical Neuroscience, Imperial College, London, United Kingdom

Resting state networks undergo various age related changes both in strength and spatial distribution. Some occur in adolescence while many changes also occur later in adulthood. A salience network splits without much strength in any age group. These different findings reflect multiple normal ageing processes of the central nervous system.