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Abstract #2075

Evaluating MACC for Improved MS Rater Agreement

David S. Wack1, Michael G. Dwyer1, Niels Bergsland1, Sara Hussein1, Robert Zivadinov1

1University at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, NY, United States

The software method of Minimum Area Contour Change (MACC) is evaluated for use to improve same scan inter-rater agreement for the delineation of T2 hyper-intense MS lesions; and for the application of ROIs to follow up time points. The MACC method improves inter-rater agreement, and performs about on par with another rater for the purpose of drawing lesion ROIs on a follow-up scan.