Muftah Ahmed Manita1, Paul Morgan2,
Keith Robson3, Timothy Jaspan3, Dorothee P. Auer1
1Academic Radiology, University of
Nottingham, Nottingham, United Kingdom; 2Radiology & Radiological
Science, Medical University of South Carolina, United States; 3Nottingham
University Hospital, United Kingdom
Perfusion
MRI DSC (T2*) has shown added values in glioma tumour differentiation with
rCBVmax is the best performing metrics obtained from dynamic susceptibility
contrast technique (DSC). However, this technique is susceptible to blood
leak that results in rCBV overestimation. T1 MRI perfusion (DCE) is not
susceptible to vascular disruption. Nineteen patients with low and high grade
glioma underwent MR perfusion (T1 and T2*) was analysed with Java image
software. Significant difference (P=0.000) with excellent correlation (0.81)
between the two tumour grades in both techniques with accuracy of 100%. T1
based DCE is robust technique to follow postoperative cases.
Keywords