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Abstract #2191

Translational Methods for Retrospective Long Term Evaluation of Cancer with MRS

Dee H. Wu1, Levi Garrett1, Jignesh Modi1, Bowei Han1, Hans Cao1

1Radiological Center, University of Oklahoma Health Sciences Center, Edmond, OK, United States


We have created a procedure for retrospective review of digitized MRS images that permits fundamental baseline removal and frequency bracketing with the target of creating a user-friendly tool. This newly created clinical workflow will improve long term care for patients that may require important decisions pertaining to whether the status of a tumor has changed (such as tumor reoccurrence or remission). A central concept is that we have also conducted tolerance testing in which common confounds to artifacts that arise from shimming, electronic noise, field inhomogenity, coil sensitivities, relaxation.