Translational Methods for Retrospective Long Term Evaluation of Cancer with MRS

Dee H. Wu¹, Levi Garrett¹, Jignesh Modi¹, Bowei Han¹, Hans Cao¹

We have created a procedure for retrospective review of digitized MRS images that permits fundamental baseline removal and frequency bracketing with the target of creating a user-friendly tool. This newly created clinical workflow will improve long term care for patients that may require important decisions pertaining to whether the status of a tumor has changed (such as tumor reoccurrence or remission). A central concept is that we have also conducted tolerance testing in which common confounds to artifacts that arise from shimming, electronic noise, field inhomogenity, coil sensitivities, relaxation.