Jean-Marc Constans1,2, Franois Kauffmann3,
Gabriela Hossu4, Weibei Dou5, Jean-Michel Derlon6,
Emmanuelle Lechapt-Zalcmann7, Samuel Valable8,
Jean-Sebastien Guillamo9,10
1MR Unit, CHU de CAEN, CAEN, Normandy,
France; 2CERVOxy, Cyceron- CI-NAPS- CNRS , CAEN, Normandy, France;
3LMNO- UMR 6139, CNRS, CAEN, France; 4UMR 947, CIC-IT
et INSERM, Nancy, France; 5Electronic, Tsinghua University,
Beijing, China; 6CHU de Caen, CAEN, France; 7CHU de
Caen, Caen, France; 8Cyceron CINAPS CNRS UMR 6232, CAEN, France; 9CHU
CAEN, France; 10CERVOxy, Cyceron CNRS CI-NAPS, CAEN, France
MRS
with Cho/Cr, mI/Cr and NAA/Cr ratios, could be more sensitive than MRI and
could, in some cases, be predictive of worsening in gliomatosis follow-up.
These spectroscopic changes occurred well before clinical deterioration.
There is a large variability, but repetition and modelisation of
spectroscopic measurements during longitudinal follow-up could allow us to
diminish it and to improve gliomatosis prognostic evaluation.
Keywords