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Abstract #2223

Correlation Study of Cerebral Blood Flow and EEG Feature Based on CO2 Stimulation

Jing Wang1, Liu Chen1, Bing Wu2, Xiaoping Hu3, Xiaoying Wang, 12, Jue Zhang1,4, Jing Fang1,4

1Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China; 2Dept. of Radiology, Peking University First Hospital, Beijing, China; 3Dept. of Biomedical Engineering, Georgia Institute of Technology / Emory University, Atlanta, United States; 4College of Engineering, Peking University, Beijing, China

The MR based evaluation of cerebral blood flow (CBF) plays an important role in assessment of post-stroke rehabilitation, but limits by its inconvenient and high costs. In this study, the weighted average accuracy index (WAAI), as a novel electroencephalogram (EEG) feature related index was introduced to estimate effectively the change of EEG pattern with the gradual CBF improvement due to the increase of CO2 concentration. Group results of healthy subjects showed that there existed a strong relationship between WAAI and CBF, indicating that the proposed WAAI index could be helpful to evaluate the extent of brain perfusion recovery.