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Abstract #2234

Diffusion Tensor Echo Planar Imaging of Mouse Brain After Brief Focal Middle Cerebral Artery Occlusion at 14T

Hongxia Lei1,2, Yohan Van de Looij1,3, Nicolas Kunz1,3, Carole Berthet4, Lorenz Hirt4, Rolf Gruetter1,5

1LIFMET, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 2Radiology, University of Lausanne, Lausanne, Switzerland; 3Pediatrics, University of Geneva, Geneva, Switzerland; 4Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; 5Radiology, University of Geneva, Geneva, Switzerland

Diffusion tensor imaging allowed accurately measuring ADC, which is very essential for stroke studies. We sought to establish feasibilities of EPI-version DTI of mouse brain after brief ischemia at 14T. The nearly artifact free DTI images allowed accurately measuring ADC maps and help localizing ischemic core more precisely when no abnormal T2 contrast expressed.