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Abstract #2247

Magnetic Resonance Angiography of the Mouse Cerebrovascular System at 1

Firat Kara1, Alia Alia1

1Leiden Institude of Chemistry, Leiden University, Leiden, Netherlands

As magnetic field strength increase toward higher fields , it allows significant improvements in MRI techniques by enhancing contrast to noise and signal to noise ratio. The use of magnetic resonance angiography (MRA) in ultra high magnetic field to visualize cerebrovascular structure of animals, promote development of early diagnosis and treatment of human neurodegenerative diseases. In this study, an improved contrast-to-noise ratio at 17.6 T imaging contribute to visualization the smaller vessels of the mouse brain. Branches of anterior cerebral artery (ACA)are better depicted on maximum intensity projections(MIP) with 17.6 T imaging than MIPs obtained with 9.4.