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Abstract #2260

Complex Flow Patterns in a Real-Size Intracranial Aneurysm Phantom: A PC-MRI Study Compared with PIV

Pim van Ooij1, Annetje Gudon2, Christian Poelma3, Joppe J. Schneiders4, Charles B. Majoie4, Jenny Dankelman2, Ed vanBavel1, Aart J. Nederveen4

1Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Noord-Holland, Netherlands; 2Biomechanical Engineering, Delft University of Technology, Delft, Netherlands; 3Laboratory for Aero and Hydrodynamics, Delft University of Technology, Delft, Netherlands; 4Radiology, Academic Medical Center

To validate 4D blood flow velocity measurements in intracranial aneurysms using phase contrast MRI, a real-size glass phantom of an intracranial aneurysm was created and used for blood flow velocity measurements using PC-MRI and PIV. Resolution of PC-MRI was 0.5x0.5x0.5 mm and took 70 minutes to scan. Both steady and pulsatile flow measurements in MRI and PIV produced similar flow patterns of similar magnitude, although more noise was found in the MR results. Velocity to noise ratio will improve with more accurate velocity encoding settings. More importantly, to be able to apply the PC-MRI scan in patients, scan time needs to be shortened severely, for example by acceleration techniques.