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Abstract #2415

Parotid Sparing Volume-Dependent Perfusion Characteristics of Acute Radiation Injury: Investigated by Fat-Saturated Dynamic Contrast-Enhanced MRI

Cheng-Chieh Cheng1, Chun-Jung Juan2, Hsiao-Wen Chung, 2,3, Yee-Min Jen2, Su-Chin Chiu1, Hing-Chiu Chang, 1,4, Hui-Chu Chiu5,6, Cheng-Hsien Hsu2,7, Guo-Shu Huang2, Cheng-Yu Chen2

1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 2Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 3Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 4Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan; 5Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan; 6EMBA in Global Chinese Management, Department of Business Administration, Tamkang University, Taipei, Taiwan; 7Division of Software Design, Notebook Unit 5, Quanta Computer Inc., Taipei, Taiwan

Parotid glands are highly radiosensitive, while the utilization of parotid sparing technique decreases the irradiation, and thus may reduce radiation therapy damage. In this study, we demonstrate a graded alteration in the perfusion characteristics of parotid glands, with the respect of parotid-sparing volume provided by the intensity modulated radiotherapy (IMRT) technique.