High-Field in Vivo 1H-MR Spectroscopy of the Injured Mouse Spinal Cord. Feasibility and Potentiality.

Virginie Callot¹, Guillaume Duhamel¹, Mohamed Tachrount¹, Yann Le Fur¹, Patrick J. Cozzone¹

Non invasive investigations of the mouse spinal cord pathologies are currently based on anatomic and diffusion MRI. In this work, we investigated whether high-field MR Spectroscopy would be able to provide complementing biochemical information useful to describe the lesion and the repair processes. This preliminary study demonstrates the feasibility of longitudinal follow-ups with localized 1H-MRS in injured mouse spinal cord.