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Abstract #2464

High-Field in Vivo 1H-MR Spectroscopy of the Injured Mouse Spinal Cord. Feasibility and Potentiality.

Virginie Callot1, Guillaume Duhamel1, Mohamed Tachrount1, Yann Le Fur1, Patrick J. Cozzone1

1Centre de Rsonance Magntique Biologique et Mdicale (CRMBM), CNRS, UMR 6612, Facult de Mdecine, Marseille, France

Non invasive investigations of the mouse spinal cord pathologies are currently based on anatomic and diffusion MRI. In this work, we investigated whether high-field MR Spectroscopy would be able to provide complementing biochemical information useful to describe the lesion and the repair processes. This preliminary study demonstrates the feasibility of longitudinal follow-ups with localized 1H-MRS in injured mouse spinal cord.