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Abstract #2467

Bone Marrow Perfusion Magnetic Resonance Imaging in Patients with Osteoporotic Vertebral Compression Fractures: Peak Enhancement Ratio Is an Independent Predictor for Intraosseous Vacuum Phenomena

Wei-Che Lin1,2, Hsiu-Ling Chen1, Yu-Fan Cheng1, Chun-Chung Lui1

1Department of Diagnostic Radiology, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Taiwan; 2Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, Taiwan


Decrease bone marrow perfusion as reflected by lower peak enhancement ratio (PER) value in dynamic contrast-enhanced MRI (DCE-MRI) can independently predict the presence of intraosseous cleft in patients with osteoporotic vertebral compression fractures.DCE-MRI can help distinguish the more frail patients after VCF suitable for more tailored anti-osteoporotic therapy and can also identify delicate osteoporotic patients for advance treatment before an injury can occur.