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Abstract #2507

Time-Resolved Lung Perfusion- And Ventilation-Weighted MRI by Wavelet Analysis

Grzegorz Bauman1,2, Julien Dinkel3, Michael Puderbach3, Lothar Rudi Schad2

1Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany; 2Computer Assisted Clinical Medicine, University of Heidelberg, Mannheim, Germany; 3Department of Radiology, German Cancer Research Center, Heidelberg, Germany

Non-contrast based assessment of the pulmonary function using MRI remains challenging. We propose a novel post-processing method based on the Wavelet analysis to retrieve information about pulmonary perfusion and ventilation. The method utilizes rapid acquisition of time-resolved MR-data using a 2D Steady-State Free Precession sequence implemented on a 1.5 T whole-body MR-scanner. Wavelet transform allows for a robust analysis of non-stationary physiological signals (respiratory/cardiac cycles). The aim of this study was to show feasibility of the proposed approach.