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Abstract #2558

Motion-Corrected PO2 Mapping in Human Lungs Using Hyperpolarized Xe-129 MRI

G. Wilson Miller1, John P. Mugler III1, Talissa A. Altes1, Isabel Dregely2, Iulian Ruset3, Steve Ketel3, Jeff Ketel3, William F. Hersman2,3, Kai Ruppert1

1Radiology, University of Virginia, Charlottesville, VA, United States; 2Physics, University of New Hampshire, Durham, NH; 3Xemed LLC, Durham, NH

Lung pO2 mapping using hyperpolarized Xe-129 was performed in 6 healthy volunteers and 4 disease patients. An image registration algorithm was used to correct for subject motion during the breath hold acquisition.