1Radiology, University of Wisconsin,
Madison, WI, United States; 2Radiology, Medical Physics,
Biomedical Engineering, and Medicine, University of Wisconsin, Madison, WI,
United States
Gadolinium
based contrast agents Gd-EOB-DTPA and Gd-BOPTA have hepatobiliary excretion
and tremendous utility for liver lesion characterization and biliary imaging
with T1 weighted imaging. Unfortunately, most T1 weighted sequences are not
optimized for maximizing CNR in delayed phase hepatobiliary imaging. The
purpose of this study was to perform flip angle optimization at 3.0T for
delayed hepatobiliary phase imaging as part of a cross-over study comparing
Gd-EOB-DTPA and Gd-BOPTA. Data show that imaging at 40-45 FA with
0.05mmol/kg Gd-EOB-DTPA at 20 minutes and 20-25 FA with 0.1mmol/kg Gd-BOPTA
provides optimal CNR behavior to visualize the liver and bile ducts.
Keywords