Andrew Brian Gill1, Lorenzo Mannelli1, Peter Beddy1, Richard T. Black1, Ilse Joubert1, Andrew N. Priest1, Martin J. Graves1, David J. Lomas1
1Dept of Radiology, University of
Cambridge & Addenbrooke's Hospital,
This study reports hepatic perfusion measurements made with DCE-MRI at 3T, performed so as to allow analysis using a dual-input kinetic model which separates perfusion components from the hepatic artery and portal vein. DCE data acquisition had a single-heartbeat time resolution and employed a dual saturation-recovery sequence to sample high [Gd] in the blood near-simultaneously with low [Gd] in the liver parenchyma. Mean results for total perfusion (69 24 ml/min/100ml) and arterial fraction (16 7 %) from 7 healthy volunteers were in line with those reported by other groups collecting data at 1.5T.