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Abstract #2640

In Vivo Repeatability of Liver Fat Measurement Using 1H MR Spectroscopy

Gavin Hamilton1, Michael S. Middleton1, Takeshi Yokoo1, Masoud Shiehmorteza1, Claude B. Sirlin1

1Department of Radiology, University of California, San Diego, San Diego, CA, United States

We examined the repeatability of the liver fat fraction given by MR Spectroscopy. We measured the fat fraction at 3T in vivo by collecting five single average STEAM spectra at progressively longer of TEs of 10, 15, 20, 25 and 30 ms in a single breath-hold to generate T2 and T2-corrected peak areas. We repeated this measurement three times per subject and showed this method produced highly repeatable liver fat fraction and water T2 estimates. This method did not produce a repeatable estimate of fat T2.