Meeting Banner
Abstract #2656

Relaxation Time Effects in Intra Voxel Incoherent Motion Imaging

Andreas Lemke1, Frederik Bernd Laun2, Dirk Simon3, Bram Stieltjes4, Lothar Rudi Schad1

1Department of Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany; 2Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany; 3Software Development for Integrated Diagnostics and Therapy, German Cancer Research Center, Heidelberg; 4Department of Radiology, German Cancer Research Center, Heidelberg, Germany

The DWI signal was measured as a function of the b-value in the pancreas using three different echo times (TE=50, 70, 100 ms) from six healthy volunteers. A modified equation incorporating relaxation effects was introduced and parameters derived from this equation were compared to the original IVIM equation. The perfusion fraction f increased significantly with increasing echo time (P=0.0025) whereas the relaxation time compensated perfusion fraction f' showed no significant dependence on TE (P=0.31). The relaxation time compensation had no influence on the diffusion coefficients.