Abstract #2697

Evaluation of Radiotherapy Using Manganese-Enhanced MRI (MEMRI)

Shigeyoshi Saito^1,2, Sumitaka Hasegawa, Takako Furukawa, Tetsuya Suhara, Iwao Kanno, Ichio Aoki

¹Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan; ²National Institute of Radiological Sciences, Chiba, Japan

Radiotherapy is the use of high-energy x-rays or particles to treat malignancies with the intention of destroying or inactivating cells while preserving normal tissue integrity. We found demonstrated that MEMRI ; 1) Cellular viability after radiation exposure could be evaluated usingsignal enhancementmanganese-labeling was reduced after x-ray irradiation for both in-vitro and in-vivo models. MEMRI may be used to evaluate the cellular viability of tumor after radiotherapy.