Abstract #2807

Short Echo Time in Vivo Prostate MRSI

Niranjan Venugopal¹, Boyd McCurdy², Darrel Drachenberg³, Salem Al Mehari³, Aziz Alamri³, Gurudarshan Sandhu³, Sri Sivalingam³, Lawrence Ryner⁴

¹Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada; ²Medical Physics, CancerCare Manitoba, Winnipeg, MB, Canada; ³Urology, University of Manitoba, Winnipeg, MB, Canada; ⁴National Research Council Institute for Biodiagnostics, Winnipeg, MB, Canada

We present a robust method improve the quality of in vivo prostate MRSI data acquisition by utilizing an optimized conformal voxel technique coupled with a spatial-spectral excitation PRESS pulse sequence for short echo time acquisitions.The PRESS pulse sequence was modified to include the optimized conformal voxel MR spectroscopic imaging technique (CV-MRS). In vivo implementation of this optimized MRSI technique confirms the reduction in peripheral lipid contamination, and improved the quality of spectra throughout the prostate. In summary we have demonstrated the utility of short TE in vivo prostate MRSI acquisitions, which provides significant signal increase and reveal short TE metabolites to potentially improve prostate cancer detection.