Tatsuro Tsuchida1, Miwa Morikawa2, Yukihiro Umeda2, Masato Sasaki3, Tomohito Kamibayashi1, Hirohiko Kimura1
1Dept. of Radiology, University of Fukui, Fukui, Japan; 2Dept. of Respiratory Medicine, University of Fukui, Fukui, Japan; 3Dept. of Thoracic Surgery, University of Fukui, Fukui, Japan
The purpose of this study was to examine the utility of DWI-MRI for the assessment of early response to chemotherapy in patients with advanced lung cancer by comparing FDG-PET. Twenty-two lung cancer patients received MRI, FDG-PET, and CT examination before and after 1 cycle of chemotherapy. Progression-free survival (PSF) between responder and non-responder against chemotherapy was compared by means of % change of ADC and SUV. Both index indicated that responder demonstrated significant longer PSF and DWI-MRI will be a promising tool for the assessment of the early response to chemotherapy.