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Abstract #2823

Motion-Sensitized Driven-Equilibrium (MSDE) Turbo Spin-Echo Sequence Increases Radiologists' Diagnostic Performance in Detection of Brain Metastasis

Eiki Nagao1, Takashi Yoshiura1, Akio Hiwatashi1, Koji Yamashita1, Hironori Kamano1, Yukihisa Takayama1, Tuvshinjargal Dashjamts1, Makoto Obara2, Tomoyuki Okuaki2, Hiroshi Honda1

1Clinical radiology of Kyushu-university, Fukuoka, Japan; 2Philips Electoronics Japan

Motion-sensitized driven-equilibrium (MSDE) sequence has been reported to effectively suppress signals from flowing blood in vessels that can mimic the brain metastases on post-contrast T1-weighted images. We performed an observer test to determine whether use of a 3D turbo spin-echo (TSE) sequence with MSDE increases radiologistsf diagnostic performances in detecting brain metastases comparing to a conventional 3D gradient-echo sequence (MPRAGE). A jackknife free-response receiver operating characteristic (JAFROC) analysis showed that TSE with MSDE increases radiologistsf diagnostic performances compared to MPRAGE. The reading time was also significantly shortened by use of MSDE.