Optimized Single-Acquisition Lipid- And Water-Selective Imaging at High Field

William M. Spees¹, Tsang-Wei Tu¹, Sheng-Kwei Song¹, Joel Garbow¹

Side-lobe spatial-spectral excitation and frequency-selective saturation with a binomial-series RF pulse scheme were evaluated for application at high field. Both methods yield separate water- or lipid-selective images in a single acquisition. In most circumstances, the performance of the binomial saturation approach proves to be more robust. A strategy is described for overcoming unwanted artifacts arising from magnetic susceptibility mismatch in small-animal imaging.