Naoharu Kobayashi1, Hironaka Igarashi1,
Tsutomu Nakada1
1Center for Integrated Human Brain
Science, Brain Research Institute,
We
present a new method for measuring a longitudinal relaxation time, T1,
for a surface coil application utilizing adiabatic saturation pulses,
referred to here as time-optimized partial inversion recovery (TOPIR). The
recovery delays before and after the inversion pulse were optimized to sample
data points such that the total sequence time was minimized under a specified
dynamic range of the recovery curve. Accuracy of the method was validated by
comparing the values obtained utilizing conventional inversion recovery
sequence. The method enabled a two dimensional T1 mapping of a
mouse brain using a 6 point recovery curve in 2036 s.