Tandem Dual-Echo Fast Spin Echo with Inversion Recovery (Tandem-IR-DE-FSE): A Multi-Platform Pulse Sequence for Multispectral Quantitative-MRI (PD, T1, T2)

Hernan Jara¹, Stephan W. Anderson¹, Osamu Sakai¹, Jorge A. Soto¹

Purpose: There is great need for multi-spectral quantitative-MRI (qMRI) pulse sequences that can be readily implemented in MRI scanners of different manufacturers and field strengths. Methods: The Tandem-IR-DE-FSE sequences were implemented in GE (1.5T-SIGNA HDx) and Bruker 11.7T scanners. Results: Excellent directly-acquired and qMRI map image quality was obtained with both scanners: PD, T1, and T2 maps of the brain are of good image quality and also are give qMRI measures in good agreement with accepted values. Conclusion: The Tandem IR-DE-FSE sequence can produce multispectral qMRI maps of PD, T1, and T2 that are self co-registered, high spatial resolution, and with clinical coverage.