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Abstract #2976

3D Ultrashort Echo Time (UTE) Imaging in the Brain at 7T

Peder E. Z. Larson1, Duan Xu1, Daniel B. Vigneron1

1Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, United States

Ultrashort echo time (UTE) imaging of the brain has the potential for direct detection of myelin, calcifications and other short-T2 components that are altered in neurodegenerative diseases and other neurological pathologies. Ultra high-field MRI at 7T offers improved SNR for detection of these components which generally have low signal intensity. In this project, we have developed a 3D radial UTE acquisition for 7T brain imaging providing full head coverage in just over 5 mins. Both dual-echo subtraction and off-resonant saturation pulses were applied yielding good contrast of connective tissues and white matter short-T2 components.