Abstract #3118
Segmentation
of the Rat Hippocampal Mossy Fiber
Network from MEMRI Under Inhomogenous B1 Field
Way Cherng Chen1, Kai-Hsiang Chuang1
1Singapore Bioimaging Consortium,
A*STAR, Singapore, Singapore
A
method of segmenting the rat hippocampal mossy fiber network from MEMRI under
inhomogeneous B1 field was introduced. High-pass filtering was used to
correct the intensity inhomogeneity, followed by multi-level Otsu thresholding and removal of clusters
with 10 or less lpixels to obtain final segmented image. High-pass filtering
corrected for intensity inhomogeneity and enhanced the edges of the network
making it preferable to N3 correction. Comparison with manual segmentation on
5 data sets yielded a t-value of 0.390>0.05 and a true positive rate of
91.8%.
