Hendrik de Leeuw1, Mandy Conijn1, Peter R. Seevinck1, Jeroen Hendrikse2, Gerrit H. van de Maat1, Chris J.G. Bakker1
1Image Sciences Institute,
In MRI studies, magnitude images are often used as the only source of information. Especially in the presence of local field distortions, this might be considered suboptimal, since information on the local magnetic field is encoded in the signal phase. Studies that use signal dephasing only, do not allow discrimination between paramagnetic and diamagnetic disturbances, since signal dephasing is independent of the sign of the field. We will show, by analysis of microbleeds and calcifications in the brain, that by using the phase derivative, local field disturbances can be detected and analyzed in terms of positive or negative susceptibility deviations.