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Abstract #3168

Sodium Imaging of Patients After Matrix-Associated Chondrocyte Transplantation at 7 Tesla: Preliminary Results and Comparison with DGEMRIC at 3 Tesla

Siegfried Trattnig1, David Stelzeneder1, Vladimir Juras1,2, Pavol Szomolanyi1,2, Goetz Hannes Welsch1,3, Tallal Charles Mamisch4, Stefan Zbyn1

1MR Centre - High field MR, Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia; 3Department of Trauma Surgery, University Hospital of Erlangen, Erlangen, Germany; 4Department of Orthopedic Surgery, Inselspital, Bern, Switzerland

The feasibilty of sodium imaging in 12 patients after matrix-associated autologous chondrocyte transplantation was demonstrated at 7 Tesla. The repair tissue was well delineated on sodium imaging at 7T and with one exception lower normalized sodium values and thus a lower glycosaminoglycan content was found in the repair tissue compared to healthy cartilage as a reference. A good correlation between normalized sodium values at 7T and postcontrast T1 relaxation time values at 3T was found. Sodium imaging at 7T is a promising tool in the monitoring of the maturation of repair tissue after matrix-associated autologous chondrocyte transplantation.