Goetz Hannes Welsch1,2, Tallal Charles Mamisch3, Lukas Zak4, Andreas Mauerer2, Sebastian Apprich1, Michael Deimling5, Stefan Marlovits4, Siegfried Trattnig1
1MR Center, Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Department of Trauma and Orthopaedic Surgery, University Hospital of Erlangen, Erlangen, Germany; 3Department of Orthopaedic Surgery, University of Basel, Basel, Switzerland; 4Center for Joints and Cartilage, Department of Trauma Surgery, Medical University of Vienna, Vienna, Austria; 5Siemens Healthcare, Erlangen, Germany
The aim of this study was to use a recently described double-echo at steady-state (DESS-T2d) approach in an initial study to assess the morphological Magnetic-resonance Observation of Cartilage Repair Tissue (MOCART) score as well as biochemical T2-values in patients after matrix-associated autologous chondrocyte transplantation of the knee by only one sequence. The results show a good correlation in between standard morphological and multi-echo spin-echo quantitative T2 and the new DESS-T2d approach. Hence the presented hybrid sequence provides the possibility to combine morphological and biochemical MRI in one fast 3D-sequence and thus may attract for the clinical use of biochemical MRI.