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Abstract #3229

Changes in Oxidative Metabolism of Skeletal Muscle Induced by Loaded Vibration Exercise Under Vascular Occlusion

Susanne Heinzer-Schweizer1, Flurin Item2,3, Anke Henning1, Michael Wyss1, Jonas Denkinger3, Roland Kreis4, Marco Toigo2,3, Urs Boutellier2,3, Peter Boesiger1

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 2Institute of Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland; 3Exercise Physiology, Institute for Human Movement Sciences, ETH Zurich, Zurich, Switzerland; 4Department of Clinical Research, University Bern, Bern, Switzerland

Strength training has become a major component sports and rehabilitation. We have developed an exercise paradigm that combines three modalities known to positively influence strength. 21 female subjects were recruited, whereof 12 were trained. Before and after 5.5 weeks of training, oxygen consumption, lactate levels and body composition were determined, muscle biopsies were acquired, and dynamic 31P spectroscopy measurements were performed. Capillary-to-fiber-ratio, calf lean mass, peak power, resting pH, and resting inorganic phosphate and phosphocreatine concentrations changed significantly with training. A large increase in enhancement of metabolic parameters in a short time is therefore possible using this new exercise paradigm.