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Abstract #3248

Ultra-High-Resolution Skin Imaging at 7 T with Motion Correction and Fat/Water Separation

Jolle Karine Barral1, Mohammad Mehdi Khalighi2, Ron D. Watkins3, Michael Lustig1,4, Bob S. Hu, 1,5, Dwight G. Nishimura1

1Electrical Engineering, Stanford University, Stanford, CA, United States; 2Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 3Radiology, Stanford University, Stanford, CA, United States; 4Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, United States; 5Palo Alto Medical Foundation, Palo Alto, CA, United States

When high field strengths and small transmit-receive coils are used, SNR is no longer the sole limit to high-resolution imaging. Chemical shift and motion artifacts become major concerns. To address these concerns, a Cartesian gradient echo pulse sequence was designed with interleaved echoes for fat/water separation and interleaved navigators for motion correction. In vivo skin images with 100 μm isotropic resolution (1 nL) are presented. Fat/water separation allows the clear delineation of the different skin layers while motion correction effectively removes blurring.