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Abstract #3323

Localized in Vivo 13C MRS of Brain Glycogen at 9.4 and 14.1 T: A Comparison

Ruud B. van Heeswijk1, Yves Pilloud1, Florence D. Morgenthaler1, Rolf Gruetter1,2

1Laboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fdrale de Lausanne (EPFL), Lausanne, VD, Switzerland; 2Radiology, Universities of Lausanne & Geneva, Lausanne & Geneva, Switzerland

Localized 13C MR spectroscopy of rat brain glycogen at 9.4 and 14.1 T are compared. After pre-labeling at the C1 position and absolute quantification of the concentrations, the signal-to-noise ratio (SNR) of the glycogen and glucose C1 resonances are compared at the two field strengths. The T1 relaxation time and effective linewidth are also determined, and an overall comparison of the spectral quality is made.