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Abstract #3337

Relaxometry-Based Spectroscopic Differentiation of Gray and White Matter in the Human Brain: On the Stability of Tissue Water as an Internal Reference

Jack Knight-Scott1

1Radiology, Children's Healthcare of Atlanta, Atlanta, GA, United States


The spectroscopic relaxation model for brain tissue is different from the imaging relaxation model. As many as three water compartments have been detected in imaging. Here we examine the sensitivity and stability of a fast spectroscopic relaxometry technique. Specifically, we explore the stability of the spectroscopy relaxation model of human brain tissue by examining its results when applied across an aging population and across different brain regions.

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