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Abstract #3403

Gas Content Dependence in Magnetic Resonance Elastography of the Lungs

Marlies Friese1,2, Roberta Santarelli2, Lionel Martin2, Luc Darrasse2, Ralph Sinkus3, Xavier Matre2

1Center for Magnetic Resonance, The University of Queensland, Brisbane, Queensland, Australia; 2Imagerie par Rsonance Magntique et MultiModalits (UMR8081), Univ Paris-Sud, CNRS, Orsay, France; 3Institut Langevin (UMR 7587), ESPCI, Univ Denis Diderot, CNRS, Paris, France

Magnetic resonance elastography is performed in a pig lung inflated with three different gases, helium-4 (4He), air and sulphur hexafluoride (SF6), in a phantom designed for voxel-by-voxel comparison. Proton MRI morphology and computed l, Gd and Gl maps were compared on a voxel-by-voxel basis by computing mean differences between corresponding voxels. Voxel-by-voxel comparison of Morphology data and l values shows good agreement between air/4He, Air/Air and Air/SF6 measurements while Gd and Gl values agree less well. Global values of Gl, Gd and l are in excellent agreement for the different gases, showing gas density does not affect MRE measurement.