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Abstract #3438

Periventricular Areas Anti-Correlate with Visual Cortex in High Resolution Resting-State FMRI at 7T

Marta Bianciardi1, Masaki Fukunaga1, Peter van Gelderen1, Jacco A. de Zwart1, Jeff H. Duyn1

1Advanced MRI Section, LFMI/NINDS/NIH, Bethesda, MD, United States

Anti-correlation between the default mode network and an extended dorsal attention system has been previously observed in resting-state fMRI. Here we report on the presence of regions that anti-correlate with the visual cortex in resting-state fMRI at 7T. This activity occurs in proximity of the ependymal vascularization of the ventricular system, is modulated by behavioral state and is not an artifact due to head motion, heartbeat or respiration. The findings are consistent with a blood volume increase of veins downstream from visual areas.