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Abstract #3518

Discrepancy of Functional Connectivity in Sensorimotor Network Between Pre- And Post-Sleep Conditions

Po-Yu Liu1, Yu-Chin Wu2, Changwei Wesley Wu3, Chia-Ju Chen4, Ching-Po Lin1

1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; 2Institute of Nuclear Engineering and Science, National Tsing-Hua University, Hsinchu, Taiwan; 3Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 4Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan

Sleep usually refreshes our daily fatigue and rejuvenates our body, which is achieved due to physiological alterations in the sensorimotor network. However, the detailed mechanism of sleep under the brain circuit level remains unclear. To disclose the sleep effects on the sensorimotor system, the functional connectivity in bilateral primary motor cortex (M1) and supplementary motor area (SMA) were compared between Pre- and Post-sleep conditions using the resting-state fMRI. Results showed that connectivity strengths between motor areas were significantly decreased after sleep, implying a relaxing effect after an effective sleep.