Abstract #3530

Hippocampal Functional Networking in Wakefulness and Sleep

Ktia Cristine Andrade¹, Victor I. Spoormaker¹, Martin Dresler¹, Roberto Goya-Maldonado¹, Renate Wehrle², Florian Holsboer¹, Philipp G. Smann¹, Michael Czisch¹

¹Max Planck Institute of Psychiatry, Munich, Bavaria, Germany; ²Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland

Simultaneous EEG/fMRI resting state data reveal varying hippocampal functional connectivity during wakefulness and NREM sleep. Our data suggest a transition from DMN bound hippocampal connectivity during the waking state to neocortical networking during sleep stage 2. These findings may signify memory consolidation processes hypothesized to occur during sleep.