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Abstract #3530

Hippocampal Functional Networking in Wakefulness and Sleep

Ktia Cristine Andrade1, Victor I. Spoormaker1, Martin Dresler1, Roberto Goya-Maldonado1, Renate Wehrle2, Florian Holsboer1, Philipp G. Smann1, Michael Czisch1

1Max Planck Institute of Psychiatry, Munich, Bavaria, Germany; 2Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland

Simultaneous EEG/fMRI resting state data reveal varying hippocampal functional connectivity during wakefulness and NREM sleep. Our data suggest a transition from DMN bound hippocampal connectivity during the waking state to neocortical networking during sleep stage 2. These findings may signify memory consolidation processes hypothesized to occur during sleep.