Meeting Banner
Abstract #3533

The Rostral Supplementary Motor Area Supports the Repetition of Visually and Auditorily Presented Pseudowords

Gesa Hartwigsen1, Stephan Ulmer2, Annette Baumgaertner1, Hartwig Roman Siebner1,3

1Department of Neurology, Christian-Albrechts-University Kiel, Kiel, Germany; 2Institute of Neuroradiology, University Hospital of Schleswig-Holstein, Kiel, Germany; 3Danish Research Centre for Magnetic Resonance, Hvidovre University Hospital, Copenhagen, Denmark

We used functional magnetic resonance imaging to delineate areas involved in modality-independent pseudoword repetition in healthy right-handed subjects. A conjunction analysis revealed that the rostral supplementary motor area (rSMA) was activated during pseudoword repetition. Activity in the right rSMA showed increased task-related coupling with activity in the ipsilateral primary motor cortex (M1) and contralateral ventral premotor cortex (PMv) as revealed by a psychophysiological interaction. We show that rSMA is involved in modality-independent pseudoword repetition. The increased task-related influence of rSMA on M1 and PMv during pseudoword repetition suggests a supervisory role of the rSMA on executive motor areas in language production.