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Abstract #3541

BOLD Temporal Dynamics of Superior Colliculus and Lateral Geniculate Nucleus During Monocular Visual Stimulation

Condon Lau1,2, Kyle Xing1,2, Kevin C. Chan1,2, Ed X. Wu1,2

1Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China; 2Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China

The superior colliculus (SC) and lateral geniculate nucleus (LGN) are the main destinations for fibers from the optic nerves. Their functions are important for processing and responding to visual stimuli. BOLD fMRI with TR = 200ms is used to measure the temporal dynamics of the SC and LGN (of Sprague-Dawley rats) in response to monocular visual stimuli to better understand their functions. The results show that the LGN response has smaller amplitude and is delayed relative to the SC response by approximately 0.8s. This shows that the neuronal and/or hemodynamic responses in the SC and LGN are temporally different.