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Abstract #3564

MRI of Longitudinal Myocardial Strain Using Multislice Cine DENSE with Through-Plane Displacement Encoding

Xiao Chen1, Xiaodong Zhong, 1,2, Frederick H. Epstein3

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2MR R&D Collaboration, Siemens Healthcare, Atlanta, GA, United States; 3Radiology, University of Virginia, Charlottesville, VA, United States

The purpose of the present study was to develop a cine DENSE pulse sequence for quantitative imaging of longitudinal motion, where two adjacent short-axis slices are encoded for through-plane (longitudinal) displacement and are simultaneously acquired. Displacement trajectories measured from the two slices are used to calculate longitudinal strain. By acquiring both slices within a single breathhold, a fixed and consistent distance between the slices is maintained, which enables the accurate calculation of longitudinal strain from the measured longitudinal displacement fields. The sequence and theory were evaluated and demonstrated in normal volunteers.