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Abstract #3597

Quantifying Right Ventricular Motion and Deformation Using 3D Cine DENSE MRI

Daniel Alejandro Auger1, Xiaodong Zhong2, Ernesta Meintjes1, Fred Epstein3, Bruce Spottiswoode1,4

1MRC/UCT Medical Imaging Research Unit, University of Cape Town, Cape Town, Western Cape, South Africa; 2MR R&D Collaborations, Siemens Medical Solutions, Atlanta, GA, United States; 33Departments of Radiology and Biomedical Engineering, University of Virginia, , Charlottesville VA, United States; 4Radiology, University of Stellenbosch, Cape Town, South Africa.

Displacement encoding with stimulated echoes (DENSE) is a quantitative MRI technique used for measuring myocardial displacement and strain at a high spatial resolution. Studies quantifying the motion of the right ventricle (RV) have been limited by the RVs thin wall, asymmetric geometry and complex motion. A free-breathing navigator gated spiral 3D cine DENSE sequence has recently been developed, thus providing a well suited tool for capturing the complex behavior of the RV. This study involves analyzing the RVs 3D motion and strain at a previously unattainable spatial resolution. The results are consistent with previous studies using myocardial tagging.